Peptide Profiles
What Is Retatrutide? The Triple Agonist Peptide Explained
Retatrutide (LY3437943) is one peptide that activates GIP, GLP-1 and glucagon receptors. Its pharmacology, half-life and trial results.
Metabolic research
Published work on energy balance, glucose handling, lipid metabolism and the receptors involved. Each result is reported with the species and model it came from, because a rodent metabolic result and a human pharmacokinetic result are not interchangeable evidence.
Research Reviews
Retatrutide Half-Life: What Phase 1 Data Show
Retatrutide's half-life in humans is about 6 days in a phase 1b trial. How it was measured, why it is so long, and what it means for stability.
Comparisons
Retatrutide vs Semaglutide: One Receptor or Three
Semaglutide is a selective GLP-1 receptor agonist; retatrutide activates GIP, GLP-1 and glucagon receptors. Structure, half-life and trial endpoints compared.
Comparisons
Retatrutide vs Tirzepatide: Receptors, PK and Trial Data
Retatrutide adds glucagon receptor activity to tirzepatide's GIP/GLP-1 agonism. Receptors, half-life, status and trial endpoints compared.
Peptide Profiles
What Is AOD-9604? The hGH 177-191 Fragment Analogue
AOD-9604 is a 16-residue analogue of hGH 177-191 with an added tyrosine. Its structure, rodent lipid-metabolism studies and detection methods.
Peptide Profiles
What Is Cagrilintide? The Long-Acting Amylin Analogue
Cagrilintide is a lipidated, long-acting amylin analogue acting on amylin and calcitonin receptors. Its design, mechanism and phase 2 data.
Lab Handling
How to Reconstitute Retatrutide: Lab Method and Math
Reconstituting lyophilized retatrutide for research: solvent choice for a lipidated peptide, concentration tables for 5–60 mg vials, mixing and storage.
Lab Handling
How to Reconstitute Tirzepatide for In Vitro Research
Reconstituting research tirzepatide: stock solutions, mg/mL to micromolar conversion at 4813.5 Da, dilution for cell assays, low-binding plastics and storage.
Peptide Profiles
Is GLP-1 a Peptide? GLP-1, Analogues and Co-Agonists
Yes: GLP-1 is a ~30 amino acid peptide hormone from proglucagon. How native GLP-1 differs from long-acting analogues and co-agonist peptides.
Peptide Profiles
What Is Tirzepatide? Structure, Receptors and Research
Tirzepatide is a 39-residue lipidated peptide acting on GIP and GLP-1 receptors. Its structure, discovery, pharmacokinetics and key trial data.