Lab Handling
SS-31 Reconstitution, Sequence and the N-Acetyl Question
SS-31 is a cationic four-residue peptide with an unnatural amino acid. How to reconstitute it, and why the terminal form on the label matters.
Lab Handling
SS-31 is a cationic four-residue peptide with an unnatural amino acid. How to reconstitute it, and why the terminal form on the label matters.
Comparisons
SS-31 accumulates in mitochondria and binds cardiolipin; MOTS-c is encoded by mitochondrial DNA. Opposite relationships to the same organelle.
Research Reviews
The renal literature is the densest part of SS-31 research, spanning cisplatin injury, diabetic nephropathy and ageing glomeruli. A review.
Peptide Profiles
SS-31, also called elamipretide, is a four-residue cell-permeable peptide that accumulates in the inner mitochondrial membrane by binding cardiolipin.