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Peptide chemistry

What is physically in the vial, and the chemistry that decides it. These articles cover sequence and three-letter notation, salt form and counterion and why they move the weight on the label, how molecular weight relates to net peptide content, solubility and the solvents it depends on, and the synthesis and purification steps that leave the impurities a certificate later reports.

Comparisons

Is NAD+ a Peptide or a Coenzyme?

NAD+ is a dinucleotide coenzyme, not a peptide. Why it appears in peptide catalogues anyway, and what that means for how it is handled.

Jesse Brooks

Research Reviews

Dihexa Acetate: Structure, Salt Form and Naming

Dihexa is a modified angiotensin IV tripeptide carrying two hexanoyl groups. What the acetate salt means and why the mass must be checked.

Jesse Brooks

Comparisons

NAD+ to NADH: Reduction or Oxidation?

NAD+ to NADH is a reduction. Why the plus sign is not a charge on the whole molecule, and why the ratio matters more than either concentration.

Jesse Brooks

Testing & Quality

Custom Peptide Synthesis: What to Specify

A custom peptide order is a specification, not a request. Which parameters to state, which sequences are difficult, and what the quotation leaves out.

Jesse Brooks

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