Comparisons
Tesamorelin vs CJC-1295: Two Ways to Stabilise GHRH
Tesamorelin keeps all 44 GHRH residues with an N-terminal cap; CJC-1295 shortens to 1-29 and substitutes four residues. How the two strategies compare.
The hypothalamic-pituitary axis that controls growth hormone release, and the analogues and secretagogues used to study it: receptor targets, pulsatility, half-life differences between analogues, and how the axis is measured in published work.
Comparisons
Tesamorelin keeps all 44 GHRH residues with an N-terminal cap; CJC-1295 shortens to 1-29 and substitutes four residues. How the two strategies compare.
Comparisons
Sermorelin stimulates an axis; somatropin replaces its product. The difference in pulsatility, feedback and regulatory status, for research context.
Peptide Profiles
Hexarelin is a hexapeptide secretagogue with a methylated tryptophan. Its structure, acetate salt, rodent kinetics and cardiovascular literature.
Peptide Profiles
GHRP-6 is a hexapeptide secretagogue acting at the ghrelin receptor. Its sequence, acetate salt form, receptor pharmacology and published research.
Peptide Profiles
Sermorelin is GHRH (1-29), the shortest fragment of growth hormone-releasing hormone retaining receptor activity, with a literature going back to the 1980s.
Peptide Profiles
IGF-1 LR3 is a recombinant IGF-1 analogue with an N-terminal extension and an Arg3 substitution that reduces binding-protein affinity. What that changes.
Peptide Profiles
Ipamorelin is a pentapeptide ghrelin-receptor agonist and the first selective GH secretagogue: GH release without ACTH or cortisol rises in swine.
Comparisons
Tesamorelin activates the GHRH receptor; ipamorelin activates the ghrelin receptor. Structure, pharmacology, evidence base and why they are studied together.
Comparisons
Sermorelin is GHRH(1-29)-NH2; tesamorelin is full-length GHRH(1-44) with an N-terminal hexenoyl group. Structure, stability and clinical history compared.
Peptide Profiles
AOD-9604 is a 16-residue analogue of hGH 177-191 with an added tyrosine. Its structure, rodent lipid-metabolism studies and detection methods.
Peptide Profiles
CJC-1295 (no DAC) acts on the GHRH receptor and ipamorelin on the ghrelin receptor. Why they are paired, what each has been shown to do, and blend lab handling.
Peptide Profiles
CJC-1295 is a modified GHRH(1-29) analogue; the DAC version binds albumin for a 6–8 day half-life. Structure, human GH/IGF-I data, detection and handling.