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Growth hormone axis

The hypothalamic-pituitary axis that controls growth hormone release, and the analogues and secretagogues used to study it: receptor targets, pulsatility, half-life differences between analogues, and how the axis is measured in published work.

Peptide Profiles

What Is Sermorelin? GHRH (1-29) Peptide Profile

Sermorelin is GHRH (1-29), the shortest fragment of growth hormone-releasing hormone retaining receptor activity, with a literature going back to the 1980s.

Jesse Brooks

Peptide Profiles

What Is IGF-1 LR3? Long R3 IGF-1 Explained

IGF-1 LR3 is a recombinant IGF-1 analogue with an N-terminal extension and an Arg3 substitution that reduces binding-protein affinity. What that changes.

Jesse Brooks

Peptide Profiles

What Is Ipamorelin? The Selective GH Secretagogue

Ipamorelin is a pentapeptide ghrelin-receptor agonist and the first selective GH secretagogue: GH release without ACTH or cortisol rises in swine.

Jesse Brooks

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