Comparisons
Kisspeptin-10 vs Kisspeptin-54: Same Ending, Different Peptide
Both forms share the C-terminal region the receptor reads, so why is the longer one more potent in vivo? Duration, not receptor affinity.
Kisspeptin-10
Lab Handling
Kisspeptin-10 Reconstitution and Working Solutions
Kisspeptin-10 has a characterised decomposition product and short measured exposure. How to reconstitute it so the concentration is what you think.
Comparisons
Gonadorelin vs Kisspeptin: Two Steps on One Axis
Kisspeptin acts on the neurons that generate the pulse; gonadorelin is the pulse itself. Where each enters the axis and what that changes.
Peptide Profiles
How Does Kisspeptin Work? The KNDy Pulse Generator
Kisspeptin acts on KNDy neurons upstream of GnRH, where it helps generate the pulses that drive the axis. The receptor, the circuit, the evidence.
Research Reviews
Kisspeptin-10 Half-Life and Its Decomposition Product
A 2013 LC-MS/MS study measured kisspeptin-10 pharmacokinetics in rats and characterised its decomposition product. What that means for handling.
Peptide Profiles
What Is Kisspeptin-10? KISS1R Ligand Profile
Kisspeptin-10 is the C-terminal decapeptide of kisspeptin, the ligand for KISS1R. A profile of the receptor biology and the KNDy neuron literature.