Comparisons
Orexin A vs Orexin B: One Precursor, Two Reagents
Orexin A has two disulfide bridges and engages both receptors; orexin B has none and prefers OX2R. Why that makes them different reagents.
Orexin B
Peptide Profiles
What Is Orexin B? The Selective Half of the Pair
Orexin B is a 28-residue peptide from the same precursor as orexin A, but it prefers OX2R and has no disulfide bridges. The structural reasons.